Panax Ginseng

In ESMEXIL: A Traditional Healing Source with Neuroscientific Potential

Commonly known as “true ginseng,” Panax Ginseng is an herb that has been used in traditional Chinese medicine (TCM) for thousands of years. Its name is derived from the Greek word panacea, meaning “a cure for all.” Classified as an adaptogen in TCM, this root has historically been used to enhance energy, support immunity, and promote mental balance; it's believed that it helps the body cope with stress.

Bioactive Compounds and Brain-Related Effects

The primary bioactive compounds in Panax Ginseng are ginsenosides. These natural saponins may regulate signal transmission in nerve cells, activate antioxidant systems, and support neuronal balance.¹Scientific studies have explored the potential effects of these compounds on the central nervous system and have reported that, in some animal models, they contribute to processes such as synaptic plasticity, neurogenesis, and oxidative homeostasis.² ³

Possible Mechanisms Supporting Cognitive Performance

Regulation of neurotransmitter levels (acetylcholine, dopamine, serotonin)

Support for the formation of new nerve cells (in the hippocampus)

Improvement of microcirculation (cerebral blood flow)

Activation of enzymes involved in combating oxidative stress (such as SOD and GPx)

Formulated with Nano-Sized Plant-Based Structures

Panax Ginseng used in ESMEXIL is delivered through plant-based purified extracts with particle sizes smaller than 200 nanometers.⁴ These microstructures help improve bioavailability and may enable more effective delivery to the central nervous system.

Role in the ESMEXIL Formulation

Together with Coffea Arabica and Ginkgo Biloba, Panax Ginseng is one of the three core ingredients of ESMEXIL. The micro-components of these plants are formulated with modern technology to provide functional support related to the cognitive system.

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1. Ratan ZA et al. (2021). Therapeutic potential and challenges of Panax ginseng in drug delivery. Molecules.

2. Kim JH. (2018). Anti-inflammatory effects of Panax ginseng via inhibition of NF-κB in microglia. J Ginseng Res.

3. Liu L et al. (2020). Neuroprotective effects of ginsenosides: A review. Brain Res Bull.

4. Zhao B. et al. (2024). Exosome-like nanoparticles from plants. Theranostics.